IMPUTATION OF MISSING GENOTYPES WITHIN LD-BLOCKS RELYING ON THE BASIC COALESCENT AND BEYOND: CONSIDERATION OF POPULATION GROWTH AND STRUCTURE

Abstract Background Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution.The accuracy of standard imputation techniques strongly Napkin Rings depends on the similarity of linkage disequilibrium (LD) patterns in the study and reference populations.Here we develop a novel

We have studied the composition dependence of density of liquid water-DMSO mixtures at different temperatures by using the isobaric-isothermal (NPT) molecular dynamics computer simulations.The non-polarizable semi-flexible, P1 and P2 Handheld Stick Vacuum models for the DMSO molecule combined with the TIP4P-2005 water model are considered.The exces